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I have. Doesn't do anything to me. Several oral drugs don't. I believe I lack one of the enzymes needed to process it or something, I've read that a certain percent of people don't have a key liver enzyme for processing a lot of drugs.
Very interesting, could you ingest a similar enzyme and achieve the high?
What if you sublingually induct decarboxylated THC?
Im sorry to have doubted you.
But now i have questions.
Fascinating!!
The next time you get the chance, you mind trying your edibles with a fish oil chaser(not as gross as it sounds) or "bulletproof" coffee.
My assumption is that it is the enzyme comes out to breakdown fats in general and that acts as the driver in breaking down the Cannabinoids.
Coconut MCT oil as well! Ty so much!
Squee
I heard something about grapefruit juice messing with your liver enzymes so maybe that would do it for me? Also what the other commenter said below probably has some merit, the few times I have felt something from edibles it has been from an edible that is mixed with butter/some sort of fat but even then its wayyyy less of an effect than a single joint. I have tried the sublingual tinctures and they work a little bit better, presumably because they don't go through the same first-pass metabolism through my liver.
Do you smoke weed regularly? I’ve heard if you’re a regular smoker edibles won’t affect you as much. I don’t know how true that is, but It seems to be the case for me at least. Edibles have zero effect on me, at most they just make me tired but never a high or even a buzz. If I want to feel the psychoactive effects I have to smoke.
I am a fairly regular smoker so I'm sure that has something to do with it at least but even when I didn't smoke a ton they never really knocked me on my ass like some people say they do. Some of the stories I hear from people on edibles make me like "wow I wish I could be that high" :(